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    Home > Active Ingredient News > Study of Nervous System > MRI shows that decreased density of white matter veins is associated with neurodegeneration and cognitive impairment in the elderly

    MRI shows that decreased density of white matter veins is associated with neurodegeneration and cognitive impairment in the elderly

    • Last Update: 2022-10-02
    • Source: Internet
    • Author: User
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    Due to the increase in Alzheimer's disease (AD) and related dementia, age-related cognitive and functional declines are becoming more common


    In this study, the authors used WM venous density as a semi-quantitative estimate to assess the visibility


    Results of the study

    1.


    Figures 1A, C show a representative T1-MPRAGE, T2-FLAIR, and minimum intensity projection SWI (mIP-SWI)


    Figure 1 Representative images of the minimum intensity projection (mIP) of the four groups of T1-MPRAGE, T2-FLAIR, and SWI images

    Figure 2 WM vein density vs.


    2.


    Figures 3A and B illustrate a representative case of SWI images covering WMH lesion masks


    3.


    When examining the association between WM venous density and cognitive assessment, WM venous density tends


    Figure 4 Relationship between WM venous density and clinical cognitive assessment

    In this study, the authors quantitatively assessed venous oxygen saturation-dependent visibility of the WM venous vasculature on high-resolution SWI in a group of


    Previous studies have shown that decreased venous visibility and venous density on SWI images in patients with multiple sclerosis (MS) suggest that degenerative MS may lead to altered neuronal metabolism, consistent with quantitative measurements using brain oxygen metabolic rate


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