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Primary gallbladder cancer is the sixth most common gastrointestinal malignancy after colon, pancreatic, gastric, liver and esophageal cancers
.
Risk factors may include chronic Salmonella infection, exposure to chemicals used in the rubber, automotive, wood finishing and metal fabrication industries, and cholelithiasis
.
Symptoms are vague and are often associated with invasion of adjacent organs
.
The vast majority of gallbladder cancers are adenocarcinomas
.
Most patients are in advanced stage with poor prognosis
.
Imaging studies can show a mass replacing a normal gallbladder (65%), diffuse or focal thickening of the gallbladder wall (30%), or a polypoid mass within the gallbladder lumen (25%)
.
Direct involvement of the liver is seen in up to 90% of cases, followed by the colon, duodenum, and pancreas
.
Gallbladder cancer
.
Panels A-D: Upper level, as described above, with a mass that invades the liver
.
Figures E and F: The lower layer shows irregular thickening of the gallbladder wall with obvious inhomogeneous enhancement
.
Another case of gallbladder carcinoma, T2WI and enhanced delayed phase showed uneven thickening of the gallbladder wall and marked enhancement
.
Gallbladder cancer
.
The lesion invaded the liver with the gallbladder as the center, and the diffusion was obviously limited.
Because the lesion contained connective tissue/fibrous components (T2 low signal), the liver capsule was invaginated, and the enhancement scan was obviously heterogeneous in the arterial phase, and the central fibrous component was delayed in the delayed phase.
strengthen
.
Appears similar to intrahepatic cholangiocarcinoma
.
Differential diagnosis:
gallbladder wall edema
Gallbladder Wall Edema
Thickening of the gallbladder wall (with cirrhosis, portal hypertension, ascites)
.
T2WI showed that the gallbladder wall was smooth and uniformly thickened due to edema, and the enhanced gallbladder wall (inner and outer layers: mucosa and serosa) was shown in the delayed phase of enhancement, which was thin, clear and smooth
.
