Mov Disord: How does the weight change before and after Parkinson's diagnosis?

Parkinson's disease (PD) is the second most prevalent neurodegenerative disease, and its clinical diagnosis is the presence of motor dysfunction, such as bradykinesia, stiffness, tremor, and postural instability

In the United States, PD affects approximately 1 million people 65 years of age or older, and is expected to increase by 25% by 2030, thus placing an increasing burden on the health care system

A thorough understanding of these non-motor symptoms may be essential for the recognition of early disease and a better understanding of disease development

On average, compared with people without PD, the cases lost 3.

In this way, Shengfang Song and others of the University of Michigan used objective measurement methods of body composition, including total mass, muscle and fat mass, and repeated evaluations in a community-based cohort to examine the body of PD cases ten years before and after PD diagnosis.

In the Health, Aging, and Body Composition study (n = 3075; age range, 70-79 years), from year 1 to year 10, the team uses double X-ray absorptiometer can assess body composition

For each PD case in each year, they calculated the difference between the participants' actual body composition measurements and the expected value of not suffering from PD

They found 80 cases of PD

This loss is substantial and continuous, and the trends in total body weight (P = 0.

The novelty of this study is that it was discovered that a few years before the diagnosis of Parkinson's disease, the patient's weight began to drop continuously, mainly due to the decrease in fat mass

Song S, Luo Z, Li C, Huang X, Shiroma EJ, Simonsick EM, Chen H.