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    Home > Active Ingredient News > Study of Nervous System > Mol Psychiatry: The default network cortex is associated with creative thinking

    Mol Psychiatry: The default network cortex is associated with creative thinking

    • Last Update: 2022-01-23
    • Source: Internet
    • Author: User
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    Creative thinking is a major evolutionary mechanism that has contributed greatly to the rapid development of the human species


    used a new paradigm of personalized direct cortical stimulation to examine the relationship between creative thinking and DN


     

    Experimental Design Process

    Resting-state fMRI was acquired preoperatively to map individual patients' DN


    Baseline AUT performance in the operating room was positively correlated with DN integrity


    Baseline AUT performance in the operating room was positively correlated with DN integrity


    Direct stimulation of the DN's cortex impairs creative fluency


    Direct stimulation of the DN's cortex impairs creative fluency


    Using a new experimental approach, the study demonstrated a causal relationship between the default network and creative fluency by directly stimulating the cerebral cortex to disrupt separately identified regions in the default network during a divergent thinking task in awake patients


    Using a new experimental approach, the study demonstrated a causal relationship between the default network and creative fluency by directly stimulating the cerebral cortex to disrupt separately identified regions in the default network during a divergent thinking task in awake patients


    The study demonstrated that the creative fluency impairment induced by direct cortical stimulation was specific and more prominent in those participants who were stimulated in DN-related regions


    This study lays the groundwork for future interventional studies targeting associative network-related functions, which may greatly advance our understanding of the complex processes at the core of human nature


    Shofty, B.
    , Gonen, T.
    , Bergmann, E.
    et al.
     The default network is causally linked to creative thinking.
      Mol Psychiatry  (2022).
    https://doi.
    org/10.
    1038/s41380-021-01403-8 Shofty, B.
    , Gonen, T.
    , Bergmann, E.
      et al.
     The default network is causally linked to creative thinking.
      Mol Psychiatry  (2022).
    https://doi.
    org/10.
    1038/s41380-021-01403-8 et al.
    Mol Psychiatry commented

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