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Moderna initiates phase III clinical recruitment of 6900 subjects for cytomegalovirus mRNA vaccine

 Last Update: 2021-11-02
 Source: Internet
 Author: User

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Article source: Medical Rubik's Cube Info

Author: Shi Bei

On October 20, Moderna registered the efficacy, safety and immunogen of its cytomegalovirus (CMV) mRNA vaccine mRNA-1647 in 16-40 year old female healthy subjects on the US clinical trial website (ClinicalTrials.

The study plans to recruit 6900 subjects.

The mRNA-1647 developed by Moderna contains 6 mRNA sequences, including 5 mRNA encoding the pentamer complex and 1 mRNA encoding the gB antigen

Unlike protein-based vaccines, mRNA-1647 refers to the production and production of functional antigens by the body's own cells, which mimic the antigens presented by CMV to the immune system during natural infection

Cytomegalovirus (CMV) is a common pathogen that belongs to the herpes virus family

CMV infection is common in young children who have never been exposed to the virus, and is acquired and spread through contact with saliva, breast milk, mucus, and urine

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