Micro-innovation is expected to effectively treat the mezzanine of the root of the aorta

is conducting clinical research experiments with the Ping team.
Recently, Dr. Jing Jing, director of vascular surgery at Changhai Hospital, affiliated with naval military medical university, developed an original integrated valve cavity transplant and applied it further to the treatment of acute mezzanine animal models at the root of the aorta. The clinical findings are published in the Journal of the American College of Cardiology.
-litre aortic root mezzanine is the most common type of aortic mezzanine, accounting for about 60%, which is manifested in the rupture of the inner membrane of the aortic tube wall, and the tearing of the blood flow to the wall of the tube to form the true and false cavities. The false cavity affects the near end of the ascending aorta, the coronary opening, the most critical type of aortic mezzanine of the aortic valve, which can lead to aortic rupture, coronary isothermic heart attack, acute large number of aortic valve reflow to heart failure and other symptoms.
At present, the only effective treatment for the mezzanine of the root of the ascending aorta is open surgery such as open chest, deep low temperature, stop circulation, valve and aortic extensive replacement, but the risk of surgery is high, difficult, long after surgery ICU treatment time, with a certain rate of complications and mortality.
In an interview with China Science Daily, Jing said that clinically partially upgraded aortic root mezzanine patients, due to old age, infirmity, combined organ insemination or isoemia and other reasons, can not withstand traditional open surgery, and thus can not be effectively treated, "which prompted us to take the lead for these acute patients to explore new methods of in vitro minimally invasive treatment."
previously, Jing in Ping team has originally put forward a new idea of the left chamber outflow as a near-end anchoring area, and the in vitro experimental research proved feasible, to solve the problem of near-end anchoring area. Therefore, the team further used electro-electroculsive CT angioid, measuring the left culvert outflow and aortic root dynamic deformation, and accumulated a series of basic data.
on this basis, the newly published study used an integrated minimally invasivable replacement of the heart aortic valve and reconstructed the double coronary sinuses through a double window, thus completely isolating the mezzanine while ensuring the blood supply of the double-sided coronary veins.
"This is the first effective exploration of the world-leading problem of the invasive treatment of acute mezzanine at the root of the aortic in the cavity." Jing told China Science Daily that the advantage of this new method over traditional open surgery is that there is no need to open the chest, in vitro circulation and deep low temperature, can repair ruptured ascending aorta and heart valves in one-time cavity, so the physiological impact on the patient's whole body is minimal.
In addition, this method can restore as much as possible all isothermic brain, internal organ and limb blood supply in one operation, solve the problem that traditional open surgery can not restore far-end internal organs and limb blood supply, and provide new minimally invascopic invasional treatment strategies for patients with high-risk ascending aortic root mezzanine. "This will greatly shorten postoperative ICU treatment and overall recovery time and restore the patient's social and family life as quickly as possible." Jing said in Ping.
," said Valentin Fuster, editor-in-chief of the Journal of the American College of Cardiology and former president of the World Heart Alliance. (Source: Xin Yu, China Science Journal)
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