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Miao Peng's research group from Suzhou Institute of Medical Technology has made progress in the construction of fluorescent logic gates based on silver nanoclusters

 Last Update: 2022-08-15
 Source: Internet
 Author: User

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Recently, the research group of Miao Peng from Suzhou Institute of Medicine and Technology has developed a fluorescent logic gate system based on silver nanoclusters ( AgNCs ) for the simultaneous detection of telomerase and miRN.

FigureSchematic diagram of fluorescent logic gate based on AgNCs and hybridization chain reaction for detection of miRNA and telomerase

By quantitative analysis, the detection limits of miRNA and telomerase were 8 pM and 2 cells , respectivel.

This work was funded by the National Key R&D Program ( 2017YFE0132300 ) and other projects, and the results have been published in Nanoscale , 2022 , 14 , 612–616 (IF=79)

Paper link : https://pu.

FigureConfocal images of logic gates in HeLa cells after sequential addition of graphene oxide @AgNCs , auxiliary chains and telomerase inhibitors

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