Medicinal grade peanut oil use properties

Medicinal grade peanut oil use properties Peanut oil as an excipient used in pharmaceutical preparations is mainly used as a solvent
for intramuscular sustained release injections.

It can also be used as an excipient in topical pharmaceutical preparations and as a solvent
for vitamins and hormones.

It has also recently been used in pellet extended-release formulations, nasal drug delivery systems and controlled-release injections
.

Therapeutically, emulsions containing peanut oil are often used as nutrients, enemas to soften stools, and ear drops
to soften earwax.

It can also be taken orally (usually with sorbitol) as a gallbladder emptyer before gallbladder
photography.

Peanut oil is also widely used as a cooking oil
.

【Inspection】 Acidity Rancidity Take 1ml of B solution (1→10) of this product, add 1ml of hydrochloric acid, add solution (1→1000) 1ml, shake, the acid layer should not appear red or pink
.

Non-saponific compound Take 5.
0g of this product, measured according to law (General Principle 0713), and the non-saponific substance shall not exceed 1.
0%.
Impurities Take about 20g of this product, use No.
3 or No.
4 vertical molten glass crucible, measured according to law (General 0713), and the residual residue shall not exceed 0.
05%.
Alkaline impurities Take this product, determine according to law (general 0713), consume the volume of hydrochloric acid titration solution (0.
01mol/L) shall not exceed 0.
1ml
.

Methoxyaniline value (for injection) Take 2.
0g of this product, measured according to law (general 0713), methoxyaniline value should not be greater than 7.
0
.

Cottonseed oil Take 5ml of this product, place it in a test tube, add 1% sulfur carbon disulfide solution and amyl alcohol isosplex mixture 5ml, place it in a saturated sodium chloride water bath, pay attention to slow heating until the foam stops (remove carbon disulfide), continue to heat for 15 minutes, should not appear red
.

Moisture shall not exceed 0.
1% (General 0832, Act 1 2
).

Heavy metals Take 4.
0g of this product, place it in a 50ml porcelain evaporation dish, add 4ml of sulfuric acid, mix well, slowly heat until the sulfuric acid is exhausted, add 2ml of nitric acid and 5 drops of sulfuric acid, heat it on low heat until the nitrogen oxide gas is exhausted, burn at 500 ~ 600 ° C to make it completely ashed, let it cool, check according to law (general 0821 second law), contain heavy metals shall not exceed 10 parts
per million.

Fatty acid composition Take 0.
1g of this product, measured according to law (general rule 0713); respectively, take methyl myristate, methyl palmitate, methyl palmitate, methyl stearate, methyl oleate, methyl linoleate, methyl linoleate, methyl arachidate, methyl eicocenoate, methyl eicosalate, methyl behexanoate, methyl docosaenoate, methyl tetracosanoate, add n-heptane dissolved and diluted to make a solution containing 0.
1mg per 1ml, as a
。
According to the area normalization method in terms of peak area, saturated fatty acids containing less than fourteen carbon shall not exceed 0.
1%, myristic acid shall not exceed 0.
2%, palmitic acid shall be 7.
0% to 16.
0%, palmoleic acid shall not exceed 1.
0%, stearic acid shall be 1.
3% to 6.
5%, oleic acid shall be 35.
0% to 72.
0%, linoleic acid shall be 13.
0% to 43.
0%, linolenic acid shall not exceed 0.
6%, and arachidic acid shall be 0.
5% to 3.
0%.
Eicosaenoic acid should be 0.
5% to 2.
1%, beemic acid should be 1.
0% to 5.
0%, docosaenoic acid should not exceed 0.
5%, tetracosanoic acid should be 0.
5% to 3.
0%.