Medicinal grade dipotassium hydrogen phosphate cas7758-11-4 use

Medicinal grade dipotassium hydrogen phosphate cas7758-11-4 uses dipotassium hydrogen phosphate as colorless flakes or needle crystals or white particles
.

Deliquescent, easily soluble in water (1g soluble in about 3mL of water), aqueous solution is weakly alkaline, 1% aqueous solution pH is about 9, insoluble in ethanol
.

Density 2.
33 g/cm3
.

It can be used as analytical reagents, pharmaceutical raw materials, buffers in the food industry, chelating agents, yeast foods, emulsified salts, antioxidant synergists Properties and stability 1.
Used as corrosion inhibitors for antifreeze, nutrients for antibiotic media, phosphorus and potassium regulators in the fermentation industry, feed additives, etc
.

Used as water quality treatment agent, microorganism, fungal culture agent, etc
.

In the food industry, it is used in the preparation of alkaline water raw materials, fermentation agents, flavoring agents, leavening agents, milk, mild alkaline agents for products, yeast food materials
.

Used as a buffer, chelating agent
.

2.
The food industry is used as raw materials for the preparation of alkaline water for pasta products, fermentation agents, blending agents, leavening agents, mild alkaline agents for dairy products, and yeast food materials
.

It can be used as a buffer clamping agent and can also be used as a feed additive
.

3 Phosphoric acid gas two bells in the chemical analysis of electrical work buffer, used in the metal Jiehua external theory and used as an electroplating additive [check] alkalinity Take 1.
0g of this product, add water 20ml after dissolution, according to law (general rule 0631), the pH value should be 8.
5 ~ 9.
6
.

The clarity and color of the solution Take 1.
0g of this product, add 10ml of water to dissolve, check according to law (General 0901 and General 0902), the solution should be clear and colorless
.

Chloride Take 2.
5g of this product, check according to law (General 0801), and compare with the control solution made of 5.
0ml of standard sodium chloride solution, it shall not be more concentrated (0.
002%)
.

Sulfate Take 2.
0g of this product, add water to dissolve it into about 40ml, adjust the pH to slightly acidic (pH≤6) with hydrochloric acid, check according to law (General Rule 0802), and compare with the control liquid made of standard potassium sulfate solution 2.
0ml, not to be more concentrated (0.
01%)
.

Carbonate Take 2.
0g of this product, add 10ml of water, boil, cool, add 2ml of hydrochloric acid, there should be no bubbles
.

Condensate phosphate Take 2.
0g of this product, place in a 100ml measuring bottle, add water to dissolve and dilute to the scale, shake well
.

Take 5.
0ml into a Nalkennell cuvette tube, add dilute acetic acid 1.
0ml with acetic acid - sodium acetate solution (take 1 mol/L sodium hydroxide solution 17ml, dilute acetic acid 40ml, add water to make 100ml) 5.
0ml, add water to 15ml, add barium chloride test solution 2ml, shake well, leave at 25 °C ± 2 °C for 15 minutes, do not produce turbidity
.

Insoluble matter in water Take 10.
0g of this product, heat water 100ml to dissolve, filter with No.
4 perched glass crucible of pre-constant weight at 105 °C, precipitate with hot water 200ml 10 times washing, dry at 105 °C for 2 hours, the residual residue shall not exceed 2mg (0.
02%)
.

Reducing substance Take 5.
0g of this product, add new boiling and cold water to dissolve and dilute to 50.
0ml, measure 5.
0ml, dilute sulfuric acid 5ml and potassium permanganate titration solution (0.
02mol/L) 0.
25ml, heat in a water bath for 5 minutes, the fuchsia color of the solution must not disappear
.

Potassium dihydrogen phosphate takes the measurement result under the content determination and calculates it as follows, and the potassium dihydrogen phosphate content shall not exceed 2.
5%.
Loss on drying Take this product, dry to constant weight at 130 ° C, and the weight loss shall not exceed 2.
0% (General 0831).
Iron salt Take 1.
0g of this product, add water 20ml to dissolve, add hydrochloric acid solution (l→2) 1ml with 10% sulfosalicylic acid solution 2ml, shake well, add ammonia test solution 5ml, shake well, such as color, and standard iron solution (general rule 0807) 1.
0ml compared with the control solution made by the same method, not deeper (0.
001%)
.

Sodium (for the preparation of parenteral drug delivery preparations) Take 1.
00g of this product, put it in a 100ml measuring bottle, add water to dissolve and dilute to the scale, shake well, as a storage solution for the sample; take 5ml of precision measurement, put it in a 100ml measuring bottle, dilute it with water to the scale, shake well, as a test solution; take another sodium standard solution (or take the appropriate amount of sodium chloride dried at 100~105 °C for 3 hours), dissolve it with water and quantitatively dilute it to make a solution containing 50 μg of sodium per 1ml, as a control storage solution; precision dose of the test stock 5ml and the control storage liquid 1ml, placed in the same 100ml measuring bottle, diluted with water to the scale, shake well, as a control solution
。
Take the test solution and the control solution, according to the atomic absorption spectrophotometry (general rule 0406 second method), with the flame as the atomizer, measured at the wavelength of 589nm, let the reading of the control solution be a, the reading of the test solution is b, and the specified b value should be less than (a-b
).

That is, the sodium content shall not exceed 0.
1%.
Heavy metals Take 2.
0g of this product, add water 15ml to dissolve, adjust the pH of the solution with hydrochloric acid about 4, add acetate buffer (pH 3.
5) 2ml with an appropriate amount of water to make it into 25ml, check according to law (General 0821 First Law), the content of heavy metals shall not exceed 10
parts per million.

Arsenic salt Take 2.
0g of this product, add 23ml of water to dissolve, add 5ml of hydrochloric acid, check according to law (General 0822 First Law), should comply with the provisions (0.
0001%)
.