Medical grade sucrose experiment application for research and development test

Medical grade sucrose experiment declared research and development of small test sucrose ZhetangSucrose C12H22O11 342.
30 [57-30-1][1] This product is β-D-furan fructosyl-α-D-pyrran glucoside
.

【Properties】This product is a loose powder
with colorless crystalline or white crystalline properties.

This product is extremely soluble in water, slightly soluble in ethanol, and almost insoluble
in absolute ethanol.

Specific curl Take this product, weigh it precisely, add water to dissolve and quantitatively dilute to make a solution containing about 0.
1g per 1ml, determined according to law (General 0621), the specific curl is +66.
3° to +67.
0°
.

【Identification】(1) Take this product, add 0.
05mol/L sulfuric acid solution, boil, neutralize with 0.
1mol/L sodium hydroxide solution, and then add alkaline copper tartrate test solution, and heat to generate a red precipitation
of cuprous oxide.

(2) The infrared light absorption pattern of this product should be consistent with the map of the sucrose control (General 0402
).

【Check】The color of the solution Take 5g of this product, add 5ml of water to dissolve, if the color is developed, compared with the yellow No.
4 standard colorimetric solution (general rule 0901 first method), it shall not be deeper
.

Sulfate Take 1.
0g of this product, check according to law (General 0802), and compare with the control solution made of 5.
0ml of standard potassium sulfate solution, it shall not be more concentrated (0.
05%)
.

Reducing sugar Take 5.
0g of this product, put in a 250ml Erlenmeyer flask, add water 25ml to dissolve, precision add alkaline copper citrate test solution 25ml and glass beads a few grains, heat reflux to boil within 3 minutes, from the time of full boiling, continuous boiling for 5 minutes, quickly cool to room temperature (at this time should be careful not to make the bottle of copper oxide contact with air), immediately add 25% potassium iodide solution 15ml, shake well, with shaking with the slow addition of sulfuric acid solution (1→5) 25ml, After the carbon dioxide stops being released, it is immediately titrated with sodium thiosulfate titration solution (0.
1mol/L), and near the end point, add 2ml of starch indicator solution, continue to titrate until the blue disappears, and do a blank test
at the same time.

The difference in volume between the two consuming sodium thiosulfate titration solution (0.
1 mol/L) shall not exceed 2.
0 ml (0.
10%)
.

Blazing residue Take 2.
0g of this product, check according to law (General Rule 0841), and the residual residue shall not exceed 0.
1%.
Calcium salt Take 1.
0g of this product, add 25ml of water to dissolve, add ammonia test solution 1ml with ammonium oxalate test solution 5ml, shake well, place for 1 hour, and calcium standard solution (precision weigh calcium carbonate 0.
125g, put in 500ml measuring bottle, add water 5ml and hydrochloric acid 0.
5ml to dissolve, add water to the scale, shake well
.

Each lml is equivalent to 0.
10 mg of Ca) 5.
0 ml of control solution compared to the control solution made of no more concentrated (0.
05%)
.

Heavy metals: Take the residues left under the incineration residue and inspect them according to law (General Rule 0821 Second Law), and the heavy metals shall not exceed 5
parts per million.

【Category】Pharmaceutical excipients, flavor correctants and adhesives, etc
.

【Storage】Sealed and stored
in a dry place.