Matters needing attention in high-purity nitrogen generators in chromatographic experiments

The high-purity nitrogen generator uses air as raw material, carbon molecular sieve as adsorbent, using the principle of pressure swing adsorption, and using carbon molecular sieve to selectively adsorb oxygen and nitrogen to separate nitrogen and oxygen
.

The influence of nitrogen generator on chromatography is often overlooked, that is, the switching power supply in the generator will cause certain interference to the grid voltage (the start and stop of the compressor will also), so the chromatograph must be powered by a regulated power supply.
, Of course, there are very few users who do not need a regulated power supply
.

For chromatography, after the nitrogen generator produces nitrogen, dehydration and deoxygenation (adding a dehydration and deoxygenation tube) are required, otherwise the ECD detector will be damaged
.

For mass spectrometry, domestic nitrogen generators cannot achieve a high flow rate, so many people still use liquid nitrogen tanks to support the nitrogen flow required by LC/MS
.

It is worth reminding that the nitrogen generator can only collect air as a gas source in the laboratory or in a very close position outside the laboratory, and the air in the laboratory is often polluted, and the organic solvent content in it is due to the pretreatment process of the experiment.
Other reasons (in addition to the volatilization of the needle washing solvent of the GC and the volatilization of the mobile phase of the liquid phase) inevitably exceeded the standard
.

Before use, we should first check whether the air inlet is blocked by debris, and if any, deal with it in time; due to the service life of the sealing ring of the built-in air compressor piston of the instrument, the instrument should be closed in time after use.
Do not run the instrument without load when the air source is not connected,
etc.