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Rheumatism has existed since ancient times, as researchers have further clarified its pathogenesis and treatment mechanisms
.
In recent years, a variety of biological agents have been approved in China for the treatment of rheumatic immune diseases
Rheumatism has existed since ancient times, as researchers have further clarified its pathogenesis and treatment mechanisms
1.
Biological preparations refer to pharmaceutical preparations prepared from biological sources or/and biotechnology that have the ability to regulate the body's biological response and have biological activity
2.
3.
Injection method of biologics
Biological preparation injection method 3.
Biological preparation injection method
Most biological preparations are injected subcutaneously, and a small part are intravenous infusion
.
The injection site can be the outer side of the upper arm, the front side of the thigh, and the abdomen (the area outside the 3CM centered on the belly button).
Most biological preparations are injected subcutaneously, and a small part are intravenous infusion
4.
Treatment of common adverse reactions of biological agents
Treatment of common adverse reactions of biological agents 4.
Treatment of common adverse reactions of biological agents
The most common adverse reactions are local reactions at the injection site : including mild to moderate erythema, itching, pain and swelling, etc.
Injection site reactions usually occur within the first month of starting treatment, and occur less frequently in subsequent treatments
.
The injection site reaction lasts for an average of 3 to 5 days, and most of them can be relieved on their own
The most common adverse reactions are local reactions at the injection site : including mild to moderate erythema, itching, pain and swelling, etc.
5.
Due to the complex structure of biological agents and the extremely unstable protein, the stability of non-covalent bonds in its structure is easily destroyed by external factors (such as shaking, temperature, etc.
Changes and other factors can cause changes in protein structure
6.
Before use, the doctor screens patients according to the indications and contraindications, and evaluates the general condition of the patients
.
Such as age, physical fitness, immunoglobulin level, basic medication and comorbidities
.
Patients with weakened immune function or risk of other infections should be cautious or choose high-safety biological agents, and monitor serious infections during use
.
The nurse should ask the patient if there is any recent infection, allergies, or herpes before taking the medicine
.
Do a good job of psychological care to alleviate the patients' psychological fear of medication
.
Routine vital signs
.
.
Do a good job of psychological care to alleviate the patients' psychological fear of medication
.
Routine vital signs
.
Nurse
Strictly follow the principle of three checks and seven pairs to configure .
The 1ml syringe needle should be replaced after the subcutaneous injection of the drug solution is configured to avoid aggravating the injection pain.
After the injection, the patient is instructed to press locally for 5-10 minutes
.
During the infusion, monitor the changes in vital signs regularly, and prepare emergency medicines such as rescue vehicles
.
The 1ml syringe needle should be replaced after the subcutaneous injection of the drug solution is configured to avoid aggravating the injection pain.
After the injection, the patient is instructed to press locally for 5-10 minutes
.
During the infusion, monitor the changes in vital signs regularly, and prepare emergency medicines such as rescue vehicles
.
Strictly follow the principle of three checks and seven pairs
After medication, explain the precautions to the patient.
If the patient has local redness, swelling, pain, and itching, do not scratch to avoid infection.
Keep the skin at the injection site clean and wear loose cotton underwear
.
Patients should not be vaccinated during the medication
.
If the patient has local redness, swelling, pain, and itching, do not scratch to avoid infection.
Keep the skin at the injection site clean and wear loose cotton underwear
.
Patients should not be vaccinated during the medication
.
Explain the precautions to the patient after medication
7.
What should patients pay attention to?
What should patients pay attention to? 7.
What should patients pay attention to?
Before injecting biologics, you should consult your doctor or nurse about the precautions after injection, common adverse reactions, and treatment measures.
If you have any discomfort during or after the biologics injection, you should inform the medical staff in time
.
At the same time, the patient maintains a good attitude, combines work and rest, avoids cold and humid living environment, maintains air circulation, does not go to crowded places, and exercises appropriately
.
Get enough sleep, maintain a balanced diet, and maintain functional exercise
.
If you have any discomfort during or after the biologics injection, you should inform the medical staff in time
.
At the same time, the patient maintains a good attitude, combines work and rest, avoids cold and humid living environment, maintains air circulation, does not go to crowded places, and exercises appropriately
.
Get enough sleep, maintain a balanced diet, and maintain functional exercise
.
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