Male compatriots, please pay attention! Nanjing Medical University found that coronavirus may damage kidney and testis

Novel coronavirus (2019- nCoV) infection in Wuhan (NCIP) was reported in February 22, 2020 / BIOON /--2019 December It has posed a serious threat to public health ACE2 (ACE-2) has been proved to be one of the main receptors that mediate 2019-ncov into human cells, which also occurs in severe acute respiratory syndrome coronavirus (SARS) A number of studies have shown that in addition to respiratory system damage, some patients also have renal dysfunction or even renal damage, and the mechanism is not clear This has led to interest in whether coronavirus infection affects the urinary system and the male reproductive system Photo source: medrxiv researchers from the urology research team of Suzhou Hospital Affiliated to Nanjing Medical University recently used online datasets to analyze the expression of ACE2 in different human organs They reported above in medrxiv The results showed that ACE2 was highly expressed in renal tubular cells, interstitial cells and testicular vas deferens cells Therefore, the virus may directly bind to these ACE2 positive cells and damage the kidney and testis of patients The researchers believe that 2019-ncov patients should be given renal function evaluation and special care in clinical work, because the virus and antiviral drugs have certain toxicity to the kidney In addition, because of the potential pathogenicity of the virus to testicular tissue, clinicians should pay attention to the risk of testicular lesions during hospitalization and later clinical follow-up, especially the evaluation of fertility of young patients and appropriate intervention Reference: Jianqing Wang et al ACE2 expression in kidney and testis may cause kidney and testis damage after 2019-ncov infection Medrxiv 2020 Doi: https://doi.org/10.1101/2020.02.12.20022418