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On August 2, Luye Pharmaceutical Group announced that its self-developed new generation of vesicle monoamine transporter 2 (VMAT2) inhibitor LY03015 has submitted a clinical trial application in the United States and will soon enter the phase I clinical phase
.
LY03015 is used for the treatment of tardive dyskinesia (TD) and Huntington's disease (HD).
The Phase I clinical trial of LY03015 in the United States is a single-center, randomized, double-blind, placebo-controlled, single-dose, dose-escalating trial design, aiming to evaluate the safety of a single oral dose of LY03015 in healthy subjects , Tolerability and pharmacokinetic characteristics, and plan to enroll 120 subjects
.
In addition to the United States, clinical trials of LY03015 will also be carried out simultaneously in China