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Image: Ariel Gomez, MD, and his collaborators have found evidence that long-term use of common high blood pressure medications can lead to kidney damage
Source: Dan Addison | UVA Communications
A new kidney study from the University of Virginia School of Medicine has raised concerns that long-term use of prescription drugs commonly used to treat high blood pressure and heart failure could lead to kidney damage
Patients should continue to take these drugs, which include well-known and widely used ACE inhibitors, the researchers said
"Our study shows that renin-producing cells are responsible for the damage
Causes of kidney damage
Chronic hypertension affects 1 billion people worldwide
They found that special kidney cells called renin cells play an important role
In addition, the researchers found that long-term use of drugs that inhibit the renin-angiotensin system, such as angiotensin-converting enzyme inhibitors or angiotensin receptor blockers, had a similar effect
The researchers point out that these drugs can save patients' lives, so they stress the importance of continuing to take them
"It is important to conduct prospective, randomized controlled studies to determine the degree of function and tissue damage in patients taking medications to control blood pressure," said Ariel Gomez, MD, of the University of Virginia's Pediatrics and Child Health Research Center
Research results published
The researchers published their findings in the scientific journal JCI Insight
