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Super-resolution • subcellular level • high sensitivity
Gene Group Shanghai Beijing Biotechnology Co.
MERFISH: Multiplexed
The distribution of RNA in cells has a very important regulatory effect on its expression, so it is of great significance to study the spatial location of RNA
Chinese scientist Zhuang Xiaowei (Harvard University), an academician of the American Academy of Engineering, invented MERFISH (Multiplexed error-robust fluorescence in situ hybridization) multiple fluorescence in situ hybridization, breaking through the defect of the traditional smFISH technology flux of low throughput, which can detect up to 500 genes or more
The first to introduce
In 2021, Vizgen released the world's first commercialized MERFISH super-resolution imaging analysis system, MERSCOPE™
Based on the core MERFISH technology, MERSCOPE™ can perform super-resolution imaging of 1cm² tissues with a resolution of ≤ 100 nanometers, localize the spatial distribution of RNA in single cells, and quantify gene expression
Advantages of MERFISH spatial transcriptome technology
1.
Interactive software & visualization of data
MERSCOPE Vizualizer™, an interactive software for visualizing MERFISH data, produces a portfolio of cell partition analysis, detected transcripts, and high-resolution images that are compatible with third-party software analysis
A dedicated data analysis team can provide you with clustering results
Examples of MERFISH technical articles
Stogsdill, Jeffrey A et al.
Contact us
Gene Group Shanghai Beijing Biotechnology Co.
Gene Group Gene Co.
If you're interested, you can contact the gene people around you directly