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Liver Int: Pathological predictors of late recurrence of hepatocellular carcinoma in chronic liver disease

 Last Update: 2021-03-20
 Source: Internet
 Author: User

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Late recurrence of hepatocellular carcinoma (HCC) is considered to be a new liver cancer after chronic hepatitis.

This study investigated the clinicopathological and molecular factors that can be used to establish a nomogram to predict the recurrence of advanced HCC (2 years after radical resection).

Both the training and validation cohorts included patients with liver cancer whose main cause was hepatitis B who had undergone radical resection.

immunity

The training group and the verification group included 402 and 243 liver cancer patients, respectively, and the late recurrence rates were 18% (74/402) and 19% (47/243), respectively .

Training group and validation groups were included 402 and 243 patients with HCC, late recurrence rate was 18% (74/402), respectively, and 19% (47/243) training group and validation groups were included liver 402 and 243 For patients, the late recurrence rates were 18% (74/402) and 19% (47/243)

The nomogram based on these variables showed high reliability in both training and validation cohorts (Harrell C index: 0.

The combination of pSTAT3, pERK1/2 and SYK immune expression with high lobular inflammatory activity and liver cirrhosis (fibrosis) can predict the recurrence of advanced HCC pSTAT3, pERK1/2 and SYK immune expression and high lobular inflammatory activity and liver cirrhosis (fibrosis) ) Can predict the recurrence of advanced HCC

Original source:

Nahm Ji Hae, Lee Hye Sun, Kim Haeryoung et al.

org/10.
1111/liv.
14835">Pathologic Predictive Factors for Late Recurrence of Hepatocellular Carcinoma in Chronic Liver Disease in this message

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