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From photosynthesis to vision, light-sensitive proteins drive many key processes in biology
The new study, published Dec.
"The solution to protein structure has become quite simple," said senior author Simon Schurlin, Ph.
In particular, other methods of tracking the activity of individual molecules are too slow to reveal how proteins change shape over short periods of time, as bacteriorhodopsin does in response to light
"Until now, to study the dynamics of bacteriorhodopsin, people have used slower mutants," said Dr.
"We tracked the protein every 1.
In response to light, bacteriorhodopsin switches between on and off states
Optogenetics researchers insert genes for light-sensing molecules into neurons or other cells, allowing them to use pulses of light to change the behavior of cells
Alma P.