Leronlimab to prevent the spread of HIV: confirmed in macaques
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Last Update: 2020-07-14
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Source: Internet
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Author: User
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The biotech company CytoDyn developed the leronlimab (PRO 140) as a CCR5 antagonist with the therapeutic potential of HIV andCOVID-19CytoDyn announced today that a preclinical study has shown that leronlimab can be used as a pre-HIVprevention(PrEP) measureThe study assessed the effects of 350 mg (once a week) or 700 mg (every two months) on theofinfection in 18 macaques and found that a dose of 700 mg (every two months) completely prevented the spread of the humanimmunodeficiency virus (HIV) in the macaque rectalThese results were reported at the 23rd International AIDS Congress (AIDS 2020)Dr Nader Pourhassan, President and CEO of CytoDyn, said, "We are eager to begin clinical trials of leronlimab as PrEP to describe the effectiveness of leronlimab in HIV preventionThe current PrEP option requires a continuous daily administration, but its effectiveness is difficult to sustain in the long termLeronlimab can provide much-needed, long-lasting preventive treatment for people at risk of HIV infection."PrEP refers to a method by which people who have not been infected with HIV take specific antiviral drugs to prevent HIV infection before they develop HIV-prone behaviorHIV-prone behaviors usually include drug use, heterosexual polysexual partners and male same-sex sex
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