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Lenzilumab prevents or treats cytokine storms and neurotoxicity associated with CAR-T cell therapy

 Last Update: 2021-01-02
 Source: Internet
 Author: User

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Humanigen, a clinical biopharmaceutical company, announced today that the U.S. Patent and Trademark Office has granted the company a patent for cytokine storms and neurotoxicity in patients treated with the chilayer antigen recipient T (CAR-T) cells using lenzilumab.
patent covers the use of lenzilumab for the prevention or treatment of cytokine release syndrome (CRS) and neurotoxicity in patients treated with CAR-T cells.
Lenzilumab is combined and mesothetic with granulocyte macrophage cluster stimulation factors (GM-CSF), which is considered a key factor in triggering toxic reactions associated with CAR-T cell therapy, such as CRS and neurotoxicity.
Believe that lenzilumab may play an important role in enhancing CAR-T cell therapy, and we are committed to driving the development of lenzilumab to address cytokine storms associated with CAR-T cell therapy and other cytotherapy," said Cameron Durrant, M.D., M.D.
patent emphasizes the pioneering approach to neutrality with GM-CSF with lenzilumab."
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