Large-scale case-control study over 12 years: male infertility can double breast cancer risk!

Breast cancer is relatively rare in men, and its etiology is largely unkno.

Breast cancer is relatively rare in men, and its etiology is largely unkno.

In women, reproductive-related factors are important in breast cancer etiology but not in men, but it seems worth investigating whether male fertility is associated with male breast cancer ri.

However, research into the association of male infertility and reproductive history with breast cancer risk has been hampered by the rarity of tumo.

However, research into the association of male infertility and reproductive history with breast cancer risk has been hampered by the rarity of tumo.

During the study period, 3187 men living in England and Wales, diagnosed with breast cancer, and aged under 80, were identified, of whom 1998 (67%) were interview.

During the study period, 3187 men living in England and Wales, diagnosed with breast cancer, and aged under 80, were identified, of whom 1998 (67%) were interview.

112 cases (6%) and 80 (0%) controls reported that they had infertility problems and that they or their partners had consulted a doctor or infertility clinic (Table

112 112 cases (6%) and 80 (0%) controls reported that they had infertility problems and that they or their partners had consulted a doctor or infertility clinic (Table

However, it was not applicable for patients whose spouse was the source of infertility (OR = 86 (51-45)) or patients of undetermined source (OR = 26 (71-24.

1615 (88%) patients and 1423 (81%) controls had children (Table

1615 (88%) patients and 1423 (81%) controls had children (Table

Sensitivity analyses excluding men who were considered relatively unreliable by respondents gave similar results as above, especially for men who were themselves the cause of couple infertility ( p= 04) and men without children ( p< 00

Sensitivity analyses excluding men who were considered relatively unreliable by respondents gave similar results as above, especially for men who were themselves the cause of couple infertility ( p= 04) and men without children ( p< 00

Aggressive ( n= 1838) and orthotopic ( n= 160) tumors were analyzed separately (Table 5), and the above relationships were present and statistically significant for the former (not surprising since they were >90% of the total), But for the latter, the odds ratio is usually close to 0, and in any case not statistically significant, based on much smaller numbe.

In conclusion, this large case-control study provides strong evidence that male infertility is associated with an increased risk of breast cancer in m.

In conclusion, this large case-control study provides strong evidence that male infertility is associated with an increased risk of breast cancer in m.

The reason is uncertain and requires further resear.

 

Original source:

Original source:

Swerdlow AJ, Bruce C, Cooke R, Coulson P, Jones .

Infertility and risk of breast cancer in men: a national case-control study in England and Wal.

Breast Cancer Re.

2022;24(1):2 Published 2022 May 1 doi: 11186/s13058-022-01517.

Swerdlow AJ, Bruce C, Cooke R, Coulson P, Jones .

Infertility and risk of breast cancer in men: a national case-control study in England and Wal.

Breast Cancer Re.

2022;24(1):2 Published 2022 May 1 doi: 11186/s13058-022-01517.

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