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The clinical importance of delirium has been demonstrated as acute changes in arousal, inattention, and overall cognitive impairment, affecting 1 in 4 elderly (≥70 years of age) hospitalized patients
.
A better understanding of the relationship between baseline cognitive function, the occurrence and severity of delirium, and subsequent cognitive decline is an unmet need in public health
One in four elderly (≥70 years) hospitalized patients is affected
Baseline cognitive function was quantified using a modified cognitive status telephone interview method
.
For admitted patients, delirium was assessed daily using the Memorial Delirium Assessment Scale (MDAS)
1510 participants (median age 77 years [IQR 73-82], 57% female) were recruited between March 2017 and October 2018
.
209 participants were hospitalized in 371 episodes
Better baseline cognition was associated with a lower risk of delirium (OR=0.
Those with high baseline cognition (baseline Z-score +2.
Taken together, higher baseline cognitive function was associated with better prognosis
.
However, those with high baseline cognitive ability and delirium had the highest levels of cognitive decline
Taken together, higher baseline cognitive function was associated with better prognosis
references:
The effect of baseline cognition and delirium on long-term cognitive impairment and mortality: a prospective population-based study .
The effect of baseline cognition and delirium on long-term cognitive impairment and mortality: a prospective population-based study
