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    Home > Active Ingredient News > Antitumor Therapy > Lancet Sub-Journal: Efficacy and safety of KL-A167 in patients with recurrent/metastatic nasopharyngeal carcinoma in China

    Lancet Sub-Journal: Efficacy and safety of KL-A167 in patients with recurrent/metastatic nasopharyngeal carcinoma in China

    • Last Update: 2022-10-12
    • Source: Internet
    • Author: User
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    KL-A167 is a fully humanized monoclonal antibody that targets programmed cell death ligand 1 (PD-L1


    This is a multicenter, single-group Phase 2 trial, carried out simultaneously in 42 hospitals in mainland China, recruiting patients with non-keratinized R/M NPC who have failed after previous ≥ 2-line chemotherapy with a clear diagnosis of histology, and treated with KL-A167 900 mg (1 time/2 weeks) until disease progression, intolerable toxicity or withdrawal trial



    Between 26 February 2019 and 13 January 2021, a total of 153 patients were treated


    Baseline low plasma EBV DNA load is associated


    Together, the findings demonstrate the promising efficacy and controllable safety of


    Original Source:

    Yuankai Shi, et al.


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