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Lancet Sub-Journal: Efficacy and safety of KL-A167 in patients with recurrent/metastatic nasopharyngeal carcinoma in China

 Last Update: 2022-10-12
 Source: Internet
 Author: User

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KL-A167 is a fully humanized monoclonal antibody that targets programmed cell death ligand 1 (PD-L1

This is a multicenter, single-group Phase 2 trial, carried out simultaneously in 42 hospitals in mainland China, recruiting patients with non-keratinized R/M NPC who have failed after previous ≥ 2-line chemotherapy with a clear diagnosis of histology, and treated with KL-A167 900 mg (1 time/2 weeks) until disease progression, intolerable toxicity or withdrawal trial

Between 26 February 2019 and 13 January 2021, a total of 153 patients were treated

Baseline low plasma EBV DNA load is associated

Together, the findings demonstrate the promising efficacy and controllable safety of

Original Source:

Yuankai Shi, et al.

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