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Lancet Oncol: Active symptom control combined with FOLFOX chemotherapy can effectively prolong the survival of patients with advanced biliary cancer in second-line treatment

 Last Update: 2021-04-14
 Source: Internet
 Author: User

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Recently, The Lancet Oncology published a study in which patients with advanced biliary tract cancer who had progressed from first-line chemotherapy (cisplatin + gemcitabine) were treated with active symptom control (ACS) combined with FOLFOX regimen (leucovorin + fluorouracil + oxa) in the second-line treatment.

Screenshot of the paper publication webpage

Bile duct cancer includes cholangiocarcinoma and gallbladder cancer , accounting for less than 1% of all cancers in the world .

ABC-06 is a phase III, open-label randomized controlled study.

experiment process

Overall survival status

references

Angela Lamarca, Daniel H Palmer, Harpreet Singh Wasan, Paul J Ross, Yuk Ting Ma, Arvind Arora, Stephen Falk, Roopinder Gillmore, Jonathan Wadsley, Kinnari Patel, Alan Anthoney, Anthony Maraveyas, Tim Iveson, Justin S Waters, Claire Hobbs, Safia Barber, W David Ryder, John Ramage, Linda M Davies, John A Bridgewater, Juan W Valle.

Second-line FOLFOX chemotherapy versus active symptom control for advanced biliary tract cancer (ABC-06): a phase 3, open-label, randomised, controlled trial

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