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Two large randomized controlled trials have demonstrated the benefit of carotid endarterectomy for stroke prevention in patients with recent symptomatic carotid stenosis , and the observed benefit depends largely on the degree of stenosis.
Prevent stroke
However, recent cohort studies have shown that only modern medical treatment can reduce the risk of stroke, which has led some people to question the benefits of conventional surgical treatment.
It was unexpectedly discovered from three key clinical trials of endarterectomy to treat asymptomatic carotid stenosis that the stroke rate of drug therapy and the benefits of intervention are not related to the severity of the stenosis, which makes it difficult for patients to choose surgical treatment.
Blood vessel
From April 1, 2002 to April 1, 2017, a total of 2354 patients were continuously enrolled in OxVasc, 2178 patients underwent carotid artery imaging, of which 207 patients had at least one carotid artery bifurcation with 50-99% Asymptomatic stenosis (average age at imaging: 77.
Of the 56 studies (including 13,717 patients) identified in the systematic review, 23 of them provided ipsilateral stroke risk data (8419 patients) completely stratified by the degree of asymptomatic stenosis.
In summary, our findings confirm previous reports that the risk of asymptomatic carotid artery stenosis distal to stroke has decreased in the past few decades.
That is, the risk of asymptomatic carotid artery stenosis distal to stroke has declined in the past few decades.
Howard, Dominic PJ et al.
Risk of stroke in relation to degree of asymptomatic carotid stenosis: a population-based cohort study, systematic review, and meta-analysis.
The Lancet Neurology, Volume 20, Issue 3, 193-202 Risk of stroke in relation to degree of asymptomatic carotid stenosis: a population-based cohort study, systematic review, and meta-analysis.
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