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Lancet Neuro: Young people have a stroke if they exercise well?

 Last Update: 2021-04-13
 Source: Internet
 Author: User

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Carotid artery tear is the main cause of stroke in young and middle-aged people under 50 years of age.

Historically, clinicians are more inclined to use vitamin K antagonists for oral anticoagulation in patients with carotid artery tears.

Clinicians are more inclined to use vitamin K antagonists for oral anticoagulation in patients with carotid artery tears.

Lancet

Researchers conducted a multicenter, randomized, open-label, non-inferiority trial in 10 stroke centers in Switzerland, Germany, and Denmark.

The primary endpoint is to evaluate the clinical outcome (stroke, hemorrhage, or death) and MRI results (new ischemic or hemorrhagic) of each protocol population 14 days (clinical and MRI results) and 90 days (clinical results only) after starting treatment Brain disease).

Between September 11, 2013 and December 21, 2018, a total of 194 patients were enrolled; 100 (52%) were assigned to the aspirin group, and 94 (48%) were assigned to the vitamin K antagonist group.

21 patients (23%) in the aspirin group and 12 patients (15%) in the vitamin K antagonist group reached the main treatment focus (absolute difference 8%, non-inferiority p=0.

Thus, the results of the study did not show the non-inferiority of aspirin.

In summary, the research results support the use of vitamin K antagonists for oral anticoagulation in young and middle-aged carotid artery tear stroke patients.

The results of the study support the use of vitamin K antagonists for oral anticoagulation therapy in young and middle-aged carotid artery tear stroke patients.

references:

com/journals/laneur/article/PIIS1474-4422(21)00044-2/fulltext#%20" target="_blank" rel="noopener">Aspirin versus anticoagulation in cervical artery dissection (TREAT-CAD): an open-label, randomised, non-inferiority trial.

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