Lancet Child Health: Ear temperature 39.0 c as diagnostic criteria for reducing fever in children with chemotherapy neutrope%

Neutlyte cell-reduced fever is the most common complication of chemotherapy for cancer, and the temperature limit systos for fever is clinically differentHigher limits avoid unnecessary diagnosisRecently, the researchers compared the clinical safety differencebetween between the temperature limit of 39.0 degrees C and 38.5 degrees C in childrenstudies conducted in Switzerland, involving patients with any malignant tumor (1 to 18 years of age) who received marrow-inhibited chemotherapy that is expected to last 2 months or more, randomly received ear temperature and fever limits of 39.0 degrees C or 38.5 degrees C to diagnose neutrophil-reduced fever, confirmed patients are required to undergo emergency hospitalization, examination (including blood culture), necessary anti-fever drugs and empirical intravenous injection spree antibioticsThe main results of the study were neutrophil reduction fever rates and safety-related events (SRE) for each chemotherapy year269 patients, 48% of the patients were assigned to the 39.0 C groupOf the 360 cases of neutrophil-reduced fever, 72 (20%) were sREs (0 deaths, 16 cases of intensive care, 22 cases of severe sepsis and 56 cases of bacteremia)In patients randomly divided into 39.0 degrees C fever group, 151 cases were diagnosed with neutrophil reduction of fever (1.64 times per year), of which 22 cases (15%) were accompanied by SRE (0.24 times per year)In the 38.5-degree C group, a total of 209 diagnoses (2.03 per year) were diagnosed, of which 50 (24%) were SRE (0.49 per year)The mixed Poisson regression rate (RR) of 39.0 degrees C and 38.5 degrees C for neutrophil reduction disease and SRE was 0.56, respectively, and the relative risk of neutroperacytic hypoglycemia fever was 0.83studies have concluded that it is safe for children undergoing chemotherapy for cancer to use ear temperature 39.0 degrees C as a diagnostic criterion for reducing fever in neutrophils