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Kewan Pharmaceuticals completed the first patient administration of its anti-CD39 mAb in Phase 1 clinical trials in the United States

 Last Update: 2022-02-19
 Source: Internet
 Author: User

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TextPharmaceutical Guanlan

On January 20, Elpiscience announced that its innovative antibody drug ES002 has completed the first patient dosing in the Phase 1 clinical trial in the United States

Published data show that CD39 is a key rate-limiting enzyme on the ATP-adenosine pathway and plays a crucial role in the immune regulation of the tumor microenvironment

ES002 is a high-affinity monoclonal antibody developed by Kewang Pharmaceuticals that can efficiently block the ATPase activity of CD39 protein.

The clinical trial of ES002 in the United States is a multi-center Phase 1 clinical trial to evaluate the safety, tolerability, pharmacokinetics and pharmacodynamics of ES002 in patients with advanced solid tumors, and to initially explore its anti-tumor properties.

References:

[1] Kewang Pharma announced that the new CD39 monoclonal antibody ES002 has completed the first patient dosing in the Phase I clinical trial in the United States.

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