Just! A domestic drug spread the progress of the new crown test

Some domestic drugs have shown efficacy in clinical trials

Ammonia Yellow Capsules (containing 10mg/capsule of in vitro cultivated bovine yolk) significantly alleviated mild COVID-19 symptoms

In August 2022, The Only Professional Academic Core Journal in the Field of Antibiotics and Microbiology in China, The Chinese Journal of Antibiotics, Vol.

As the National Key Research and Development Program of the Ministry of Science and Technology (No.

The observation results showed that the clinical symptom improvement rates after treatment were 81.

Researchers from the Second Affiliated Hospital of Nanjing Medical University, Yifu Hospital Affiliated to Nanjing Medical University, and Huashan Hospital Affiliated to Fudan University conducted this controlled trial and observation, and the researchers selected 193 cases of mild coronavirus pneumonia patients with fever admitted to Shanghai Fanggang Hospital from April 2022 to May 2022, and randomly assigned them to two groups in a 1:1 ratio, including 92 cases in the treatment group and 101 cases in

Among them, the treatment group was given ammonia yellow ginseng capsules (including in vitro bred bovine yolk 10 mg/capsule), and the control group was given aminophenol pseudomaramphen tablets/ammoniamephen tablets, and the total treatment course did not exceed 7 days

The clinical manifestations of the new crown virus infection are diverse, the main symptoms are fever, general weakness, dry cough, etc.

For example, in the process of fixed-point treatment in this cabin hospital, a large number of mild patients have used antipyretic, antipyretic and other drugs

Among them, ammonia cacao huangmin capsule (including in vitro cultivated bovine yolk 10 mg / capsule) is a Combination of Chinese and Western preparations, the main components of which are: acetaminophen, caffeine, chlorpheniramine maleate, in vitro cultivation of bovine yolk, often used for cold caused by fever, nasal congestion, headache, sore throat and other symptoms

Its approved indications are relief of systemic symptoms

The effect behind the in vitro cultivation of bovine yolk

The researchers further pointed out in the article that this clinical observation initially suggests that the chinese and Western medicine compound ammonia cacao huangmin capsule (including in vitro cultivated bovine yolk 10 mg / capsule) can effectively improve the fever, headache, muscle soreness, nasal congestion, sore throat and other symptoms of the new crown virus infected people, and its effect may be related to

Previously published in the Chinese Journal of Experimental Formulary, the article "The Utility Characteristics of In Vitro Breeding Bovine Yolk on the Mouse Disease Evidence Binding Model of Human Coronavirus Pneumonia Epidemic Virus Attack Lung Evidence" pointed out:

The conclusions of the study showed that the in vitro cultivation of bovine yolk had obvious improvement effect on the pharmacological effect of the mouse composite model of human coronavirus infection and virus attack on lung evidence, which could significantly improve the behavior and excrement status of mice, reduce the lung index of model mice, improve the inhibition rate of lung index, reduce the expression of nucleic acid in mouse lung tissue, alleviate pathological damage of lung tissue, regulate immune function and inhibit the release of inflammatory factors, etc.

The "Mechanism Study on the Model of Human Coronavirus Pneumonia Wet Virus Epidemic by In Vitro Breeding Bovine Yolk" published in China Pharmacovigilance also pointed out:

In vitro breeding of bovine yolk has a significant therapeutic effect

At present, there are a variety of prescriptions in the proprietary Chinese medicines listed in China that contain bovine yolk, such as Angong bovine yellow pills, bovine yolk supernatant tablets, etc.

It is worth noting that the important medicinal ingredient of bovine yolk is bilirubin, which has the effect of clearing heat and detoxification, but the bilirubin content of artificial bovine yolk is only 0.

The National Food and Drug Administration Note [2012] No.

Among the cold medicine ammonia yellowmin capsules currently approved for marketing, only Huayang Liqing ® (including in vitro cultivated bovine yolk 10mg/capsule) produced by Jiangsu Huayang Pharmaceutical Co.
, Ltd.
upgraded the prescription artificial bovine yolk to in vitro cultivated bovine yolk
.

Multi-sectoral continued support for COVID-19 treatment drugs

With the continuous mutation of the new crown virus, from the original strain to the current globally circulating Omikejong strain, although the severe disease rate has decreased, the number of mild patients without lung performance has increased, and the transmission force has gradually increased, and the total number of sick people has increased significantly, and the anti-epidemic situation is still grim
.

In view of the epidemic situation, medical insurance and other departments continue to strengthen support
for the treatment of new crown drugs.

As early as March 21, the National Medical Insurance Bureau issued the "Notice on Effectively Doing a Good Job in the Medical Security Work of the Current Epidemic Prevention and Control", requiring all localities to timely adjust the new crown treatment drugs
included in the scope of medical insurance payment.

The document points out that for the new drugs added in the "Diagnosis and Treatment Plan for Novel Coronavirus Pneumonia (Trial Ninth Edition)", the provincial medical security departments refer to the relevant requirements and temporarily include them in the scope of payment of the medical insurance fund in the province, and the medical institutions will purchase them according to the price communicated between the enterprise and the relevant departments, and the medical insurance department will pay according to
the regulations.

At the same time, for drugs that have not yet been hung on the net, the provinces should allow medical institutions to purchase emergency use
offline first.
At present, provinces will generally give priority to newly approved new crown oral drugs to meet the procurement needs of medical institutions
.

According to the "2022 National Basic Medical Insurance, Work Injury Insurance and Maternity Insurance Drug Catalogue Adjustment Work Plan" issued by the National Medical Insurance Bureau on June 13, the drugs included in the "Diagnosis and Treatment Plan for Novel Coronavirus Pneumonia (Trial Version 9)" are expected to enter the 2022 medical insurance directory and obtain medical insurance reimbursement qualifications
.

Through this clinical trial, Huayang Liqing ® Ammonia Coffee Yellow Min Capsules (including in vitro cultivated bovine yolk 10mg/capsule) produced by Jiangsu Huayang Pharmaceutical Co.
, Ltd.
have obtained preliminary clinical research evidence, which can significantly improve the clinical symptoms of fever, sore throat, nasal congestion, headache, muscle soreness and other clinical symptoms in mild new crown pneumonia patients, with the accumulation of more and more powerful evidence-based medical evidence, under the support of diagnosis and treatment plans, national medical insurance and other related policies, it will make greater contributions to improving the accessibility of patient medication and epidemic prevention and control
。

Whether it is the research and development of innovative drugs for the new crown virus, or the basic research and clinical practice of the new use of old drugs based on clinical efficacy, the treatment exploration of the new crown virus pneumonia is still continuing, and the policy support is also consistent and clear
.