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Journal of Vascular Surgery: The prognostic effect of vascular calcification on the progression of abdominal aortic aneurysm

 Last Update: 2021-12-25
 Source: Internet
 Author: User

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At present, the maximum aortic diameter is the only clinical indicator used to predict the progression of abdominal aortic aneurysm (AAA)
.

As we all know, the risk of aneurysm rupture is related to the size of the aneurysm, so accurate monitoring of AAA expansion is essential

Abdominal aortic aneurysm

Research methods

The researchers conducted a retrospective study on 102 patients with AAA who were treated and followed up by the Department of Vascular Surgery of the Medical University of Vienna.
Abdominal CTA was performed every 6 months, with a total of 389 (Figure 1)
.

Use digitally stored CTA assessment to assess the vascular calcification (volume and score) of the inferior renal aorta and common iliac artery, and perform morphological analysis of AAA

Figure 1.
The anatomical area defined for analysis and the measured vascular calcification parameters in CTA

Figure 1.
The anatomical area and measured vascular calcification parameters defined in CTA.
Figure 1.
The anatomical area and measured vascular calcification parameters defined in CTA.

Research result

Studies have found that the increase in abdominal vascular wall calcification is inversely related to short-term AAA progression
.

Compared with the rapidly progressing AAA, the median inferior renal aortic calcification volume (1225.

Table 1.
Comparison of morphology and calcification parameters of slow (<2 mm) and rapid (≥2 mm) progression of AAA over 6 months

Table 1.
Slow (<2 mm) and rapid (≥2 mm) progression morphology and calcification parameters of AAA over 6 months Table 1.
Slow (<2 mm) and rapid (≥2 mm) AAA over 6 months ) Comparison of progression morphology and calcification parameters

Table 2.
The log-linear mixed model of AAA growth prediction takes time as the main influencing factor, and the effect of changes in vascular calcification

Table 2.
The log-linear mixed model of AAA growth prediction takes time as the main influencing factor, and the influence of changes in vascular calcification Table 2.
The log-linear mixed model of AAA growth prediction takes time as the main influencing factor, and the effect of changes in vascular calcification

Summarize

The investigators evaluated the prognostic value of vascular calcification measured by CTA on the progression of AAA
.

The increase in vascular calcification stabilizes the wall of the aortic aneurysm and may prevent progressive AAA expansion.

Original source:

Johannes Klopf, Lukas Fuchs, Rüdiger Schernthaner, et al.

The prognostic impact of vascular calcification on abdominal aortic aneurysm progression in this message

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