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Journal of stroke: Stroke caused by atrial fibrillation is treated according to the guidelines of the European Heart Association. How effective is it?

 Last Update: 2021-08-14
 Source: Internet
 Author: User

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For patients with atrial fibrillation (AF), long-term oral anticoagulant therapy can effectively reduce the risk of stroke and systemic embolism, and is the main treatment for preventing stroke recurrence

Stroke prevention

So far, there are no randomized controlled trials to assess the appropriate time to start oral anticoagulant therapy in patients with atrial fibrillation-related stroke

The study population was limited to patients with mild stroke

However, these recommendations are based on expert consensus and there is no high level of evidence

They included patients with acute ischemic stroke and atrial fibrillation from a nationwide multicenter registration (Korean ATrial fibrillaTion EvaluatioN regisTry in Ischemic strOke patieNts [K-ATTENTION]) from January 2013 to December 2015

Patients were divided into ESC guidelines matching group and non-matching group

Vascular cardiovascular events

Among the 2,321 eligible patients, 1,126 patients were matched 1:1 with the ESC guideline matching and non-matching groups

Compared with the non-matched group, the matched group treated according to the ESC guidelines had a lower risk of any recurrence stroke (1.

There were no significant differences in other secondary results between the two groups

The significance of this study is that it has found that oral anticoagulant therapy that matches the ESC guidelines is associated with a reduced risk of any stroke and ischemic stroke compared with non-matched therapy

Compared with non-matched treatment, oral anticoagulant treatment that matches the ESC guidelines is associated with a reduced risk of any stroke and ischemic stroke

Original source:
Eun MY, Kim JY, Hwang YH, et al.
Initiation of Guideline-Matched Oral Anticoagulant in Atrial Fibrillation-Related Stroke.
J Stroke.
2021 Jan;23(1):113-123.
doi: 10.
5853/jos.
2020.
03440.
Epub 2021 Jan 31.
PMID: 33600708; PMCID: PMC7900398.

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