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JNCCN: Quality of life is closely related to the prognosis of gastric cancer patients!

 Last Update: 2022-04-23
 Source: Internet
 Author: User

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Gastric cancer is the fifth most common malignancy worldwide and the fourth most common cause of cancer-related death

stomach cancer

Assessing health-related quality of life (HRQoL) in clinical trials is increasingly important as it addresses the impact of treatment from the patient's perspective

Quality of life assessment of the impact of chemotherapy and chemoradiotherapy (CRT) after neoadjuvant chemotherapy and extended (D2) lymphadenectomy on HRQoL; pretreatment HRQoL was also assessed on event-free survival (EFS) and overall survival (OS) potential prognostic significance

Research Process

Patients in the CRITICS trial were asked to complete the HRQOL questionnaire at baseline, after preoperative chemotherapy, after surgery, after postoperative chemotherapy or CRT, and at 12 months of follow-up

Changes in dysphagia and physiological function scores in two groups of patients

After postoperative (radio)chemotherapy, patients in the chemotherapy group had significantly improved physiological function (p=0.

Compared with the radiotherapy group, patients in the chemotherapy group had significantly better physical function (p=0.

Compared with the chemoradiotherapy group, the postoperative physiological function of the patients in the chemotherapy group was significantly improved, and dysphagia was significantly reduced .

Original source:

van Amelsfoort Romy M,Walraven Iris,Kieffer Jacobien et al.

Quality of Life Is Associated With Survival in Patients With Gastric Cancer: Results From the Randomized CRITICS TriaLeave

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