JNCCN: Comparison of different applications of radiotherapy and chemotherapy in elderly patients with local anal cancer

Anal squamous cell carcinoma (SCCA) is one of the common malignant tumors in elderly patients, with a median diagnosis age of 62 years
.
The incidence of SCCA has gradually increased, especially in patients ≥50 years of age, and the corresponding mortality rate has increased by nearly 5% in patients aged 60-69

.

Anal squamous cell carcinoma (SCCA) is one of the common malignant tumors in elderly patients, with a median diagnosis age of 62 years

The study is a retrospective study.

A total of 26,796 patients with I-III SCCA were collected from 2004 to 2015.

The study is a retrospective study.

research summary

research summary

For patients ≥70 years old, 49.

6% of T2N0 patients received SOC CRT, and 52.

For patients ≥70 years old, 49.

The proportion of elderly patients (≥65 years old) who received SOC CRT was lower than that of non-elderly patients (54.

Proportion of treatment in different stages and different age groups

Proportion of treatment in different stages and different age groups

The proportion of elderly patients (≥65 years old) who received single-agent chemotherapy was significantly higher than that of non-elderly patients (16.

9% vs 11.

The proportion of elderly patients (≥65 years old) who received single-agent chemotherapy was significantly higher than that of non-elderly patients (16.

The median follow-up time was 38.

Different definitions of OS in elderly patients with multiple chemotherapy drugs and single-agent chemotherapy

Different definitions of OS in elderly patients with multiple chemotherapy drugs and single-agent chemotherapy

In summary, for I-III anal squamous cell carcinoma (SCCA), the proportion of elderly patients receiving SOC CRT is lower than that of non-elderly patients

.

In summary, for I-III anal squamous cell carcinoma (SCCA), the proportion of elderly patients receiving SOC CRT is lower than that of non-elderly patients
.
However, elderly patients receiving SOC CRT can improve their prognosis
.
Therefore, it is necessary to optimize the treatment of such patients
.
For I–III anal squamous cell carcinoma (SCCA), the proportion of elderly patients receiving SOC CRT is lower than that of non-elderly patients
.
However, elderly patients receiving SOC CRT can improve their prognosis
.
Therefore, it is necessary to optimize the treatment of such patients
.
For I–III anal squamous cell carcinoma (SCCA), the proportion of elderly patients receiving SOC CRT is lower than that of non-elderly patients
.
However, elderly patients receiving SOC CRT can improve their prognosis
.
Therefore, it is necessary to optimize the treatment of such patients
.

Original source:

Original source:

Eric D Miller, Ansel P Nalin, Dayssy A Diaz Pardo, et al.
Disparate Use of Chemoradiation in Elderly Patients With Localized Anal Cancer.
J Natl Compr Canc Netw.
2021 Jun 10;1-9.
doi: 10.
6004/jnccn.
2020.
7691.
Online ahead of print.

Eric D Miller, Ansel P Nalin, Dayssy A Diaz Pardo, et al.
Disparate Use of Chemoradiation in Elderly Patients With Localized Anal Cancer.
J Natl Compr Canc Netw.
2021 Jun 10;1-9.
doi: 10.
6004/jnccn.
2020.
7691.
Online ahead of print.
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