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JCO: Quality of life for prostate cancer patients treated with docetaxel vs. abiraterone

 Last Update: 2021-12-04
 Source: Internet
 Author: User

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Docetaxel and abiraterone acetate in combination with prednisone or prednisone (AAP) can improve the survival rate of patients with locally advanced or metastatic hormone-sensitive prostate cancer when started together with standard care (SOC) androgen deprivation therapy

In the STAMPEDE trial, a group of patients were enrolled at the same time and randomly received docetaxel + SOC or AAP + SOC

Changes in overall QOL scores of patients in the two treatment groups

A total of 515 patients were included: 173 received docetaxel + SOC, and 342 received AAP + SOC

In the two years of randomization, the average modeled overall QOL score of patients receiving AAP+SOC treatment was 3.

Compared with docetaxel + standard androgen deprivation therapy, patients with locally advanced or metastatic hormone-sensitive prostate cancer treated with abiraterone acetate combined with prednisone or prednisone + standard androgen deprivation therapy within two years Reported quality of life is better.

Original source:

Hannah L.

Quality of Life in Men With Prostate Cancer Randomly Allocated to Receive Docetaxel or Abiraterone in the STAMPEDE Trial

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