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JCEM: The causal relationship between serum thyroid stimulating hormone and obesity

 Last Update: 2021-03-30
 Source: Internet
 Author: User

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Some previous epidemiological studies have explored the association between serum thyroid-stimulating hormone (TSH) and obesity characteristics.

Recently, a research article was published in the Journal of Clinical Endocrinology & Metabolism, an authoritative journal in the field of endocrine and metabolic diseases, which aims to clarify and analyze the causal relationship between serum TSH levels and obesity-related indicators (BMI and obesity).

The researchers searched the latest genome-wide association study ( GWAS ) on TSH, BMI and obesity to obtain complete statistics.

GWAS

Both IVW and MR-Egger results showed that gene-driven serum TSH did not cause changes in BMI or obesity.

Therefore, considering fT3 together, TSH can be significantly increased by gene-driven increase in BMI .

Considering fT3 together, TSH can be significantly increased by gene-driven increase in BMI

Original source:

Xichang Wang.

org/10.
1210/clinem/dgab183" target="_blank" rel="noopener">Causal Association between Serum Thyroid-Stimulating Hormone and Obesity: A Bidirectional Mendelian Randomization Study in this message

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