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JCEM: Obesity and Breast Cancer Risk

 Last Update: 2022-05-12
 Source: Internet
 Author: User

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Breast cancer (BC) is the most common malignancy worldwide, with more than 2.

Breast Cancer Diagnosis

Recently, a research article was published in the Journal of Clinical Endocrinology & Metabolism, an authoritative journal in the field of endocrine and metabolic diseases.

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The researchers synthesized the data and found that increased body mass index and weight gain were associated with an increased risk of hormone receptor-positive breast cancer after menopause

Mechanistically, various factors including altered adipokines balance, adipose tissue dysfunction, dysregulated insulin signaling, and chronic inflammation contribute to the development of breast cancer

Thus, combining metabolic health measures and body composition measures with body mass index can capture breast cancer risk more comprehensively

Combining measures of metabolic health and body composition with body mass index provides a more comprehensive capture of breast cancer risk

Original source:

Sandra Naaman, et al.

Obesity and breast cancer risk: the oncogenic implications of metabolic dysregulation

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