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Autism spectrum disorder (ASD) is a group of diseases characterized by impaired social function and repetitive behaviors
.
Their cause is largely unknown
Recently, a research article was published in the Journal of Clinical Endocrinology & Metabolism, an authoritative journal in the field of endocrine and metabolic diseases.
The study aims to investigate the relationship between the levels of leptin and adiponectin in the second trimester and umbilical cord blood of pregnant women and the offspring’s ASD.
Relationship
.
The researchers used 1164 pairs of mother and infant data, and used logistic regression analysis to assess the correlation between the levels of leptin and adiponectin in the blood and cord blood of pregnant women during the second trimester of pregnancy and ASD
.
In addition, the researchers evaluated the correlation between pregnant women's body mass index (BMI) as an exposure factor and ASD
Diagnose children
The relationship between blood and cord blood leptin and adiponectin levels and ASD in the second trimester
The cumulative incidence of ASD in this study was 3.
4%
.
The mother’s pre-pregnancy BMI (per 5kg/m2) was positively correlated with ASD.
diabetes
It can be seen that BMI before pregnancy and adiponectin levels during pregnancy may be effective indicators for monitoring the risk of autism
.
Elevated prenatal adiponectin levels may play an important role in the prevention of ASD
BMI before pregnancy and adiponectin levels during pregnancy may be effective indicators for monitoring the risk of autism
Original source:
Kyoung Eun Joung.
et al.
Maternal Mid-pregnancy Leptin and Adiponectin Levels as Predictors of Autism Spectrum Disorder: A Prenatal Cohort Study
.
JCEM.
Maternal Mid-pregnancy Leptin and Adiponectin Levels as Predictors of Autism Spectrum Disorder: A Prenatal Cohort Study In this message