Japanese Discovery of biological clock protein regulation is expected to treat sleep disorders

[Guo Guilin, special correspondent of global network in Japan] according to the Xinhua overseas Chinese News Network on March 4, in modern society, insomnia and other sleep disorders make many people deeply troubled, especially the office workers under great pressure Recently, the Japanese research team found that there are two kinds of proteins regulating the biological clock in the animal body, which play the role of accelerating and slowing down the biological clock respectively The research results are expected to play a role in the diagnosis and treatment of sleep disorders and other body clock related diseases According to Japan's Yomiuri Shimbun, a professor at Tokyo University, Yoshio Morita and other research teams found through animal experiments that there are two kinds of positive and negative proteins in the cells, which play the role of "accelerating" and "delaying" the body's biological clock, respectively, to ensure that the cells work normally in about 24 hours The research was published in the February 28 issue of the American Journal of science, cell The results of this study may play a role in the diagnosis and treatment of sleep disorders and other body clock related diseases The team found two proteins similar to the structures of fbxl3 and fbxl21 in mice, which can increase and decrease the grey protein repeatedly in about 24 hours The researchers found that "fbx13" protein can break down gray protein, making the biological clock faster "Fbxl3" protein can accumulate gray protein and slow down the biological clock In the absence of both proteins, the mouse's Action Rhythm completely collapsed a few weeks later.