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North America is facing a devastating opioid abuse crisis, with more than 6,300 opioid overdose deaths in Canada in 2020 and more than 90,000 deaths from opioid abuse
Although most clinical guidelines recommend indefinite continued treatment, retention of MOUD is low
Therefore, the purpose of this study was to determine the prescription characteristics of opioid overdose after buprenorphine tapering, and to understand how to safely tape buprenorphine is an important, patient-centered issue that could have significant implications
This population-based retrospective cohort study was conducted in adults
The results showed that among 5774 individuals, the median (IQR) age was 34 years old (28-44 years), of which 3462 (60.
Overall, in this retrospective cohort study, buprenorphine was tapered at least 1 year after treatment, with a slower rate of tapering and a lower percentage of days of dose reduction, regardless of the duration of the tapering, all associated
Original source:
Bozinoff N, Men S, Kurdyak P, Selby P, Gomes T.