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The rapid increase in the global aging population has led to an increased
Vitamin D and omega-3 (VITAL) trials were conducted to assess the efficacy
This study was conducted in 2021 as a pre-specified adjunct to the vitamin D and omega-3 (VITAL) trials, a 2×2-fold randomized clinical trial
The results showed that of the 25,871 randomized VITAL trial participants, 25,057 had sufficient data to calculate the frailty index
During the median 5-year follow-up, the mean (SD) frailty score increased to 0.
Overall, in the adjunct study of the VITAL trial, vitamin D3 and / or omega-3 fatty acid treatment did not affect the debilitation score or incidence
Original source:
Orkaby AR, Dushkes R, Ward R, et al.