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JAMA Psychiatry: Cognitive behavioral therapy significantly improves the risk of depression and depression relapse in patients with insomnia!

 Last Update: 2022-01-22
 Source: Internet
 Author: User

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Older adults with insomnia are at high risk of developing depression and depression relapse
.

Therefore, additional attention needs to be paid to preventing depression

Older adults with insomnia are at high risk of developing depression and depression relapse

This assessor-blinded, parallel-group, single-site randomized clinical trial evaluated a community sample of 431 people and recruited 291 adults 60 years or older with insomnia who were free of major depression in the past year or major health event
.

Study recruitment was conducted from July 1, 2012 to April 30, 2015

Participants were randomly assigned to 2 months of CBT-I (n = 156) or SET (n = 135)
.

The primary outcome was time to major depressive disorder diagnosed by interview and by the Diagnostic and Statistical

Diagnostic Statistics

RESULTS: Among 291 randomized participants (mean [SD] age, 70.
1 [6.
7] years; 168 [57.
7%] women; 7 [2.
4%] Asian, 32 [11.
0%] Black, 3 [ 1.
0%] Pacific Islander, 241 [82.
8%] White, 6 [2.
1%] multiracial, 2 [0.
7%] unknown), 156 were randomly assigned to CBT-I, and 135 to SET
.

A total of 140 patients (89.

Overall, 19 participants (12.
2%) in the CBT-I group and 35 participants (25.
9%) in the SET group developed episodic or recurrent major depressive disorder, with a 49% lower risk in the CBT-I group ( HR = 0.
51; 95%, CI 0.
29-0.
88; P = .
02) consistent with each subgroup
.

Compared with SET participants (26 [19.

The 49% risk reduction in the CBT-I group (HR = 0.

Treatment of insomnia with CBT-I has overall benefit in preventing the occurrence and recurrence of major depressive disorder in older adults with insomnia

references:

Prevention of Incident and Recurrent Major Depression in Older Adults With Insomnia: A Randomized Clinical Trial.

Prevention of Incident and Recurrent Major Depression in Older Adults With Insomnia: A Randomized Clinical Trial.
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