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Compared with premature babies, the risk of adverse neuropsychiatric outcomes in full-term newborns is lower, but it is not clear how the change in the age of newborns born at 37-42 weeks of pregnancy has an effect on neurodevelopment.
recently looked at the relationship between the age of birth (GAB) in children and the shape of brain structure at age 10.
study, conducted in the Netherlands, involved 3,079 newborns with GAB between 26.3 and 43.3, followed by participants aged 10 years, and GAB was calculated on the basis of an ultrasound assessment of the length of the crown hip (-lt;12 weeks 5 days) or the double-top diameter (12 weeks and 5 days).
the main endpoints of this study were brain structure, including overall and regional brain volume and surface-based cortical measurements (thickness, surface area, and brain back) quantified through magnetic resonance imaging.
50.2 per cent of the 3,079 10-year-olds in the united States.
study found that GAB was linearly associated with brain volume throughout the brain and region.
longer pregnancy is associated with larger brain volumes; for example, for every week of pregnancy extension, the total brain capacity increases by 4.5 cm3/wk.
these associations persist when only full-month-old children are considered (GAB: 4.8cm3/wk at 37-42 weeks).
there is no evidence of a nonlinear association between GA and brain morphological econometrics.
study concluded that pregnancy was linearly related to the measurement of brain morphology in childhood, and that even in full-term delivery of newborns, longer pregnancies were positively related to larger brain volumes.
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