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    Home > Active Ingredient News > Antitumor Therapy > JAMA Oncology: Sedentary life greatly increases the risk of death in cancer patients

    JAMA Oncology: Sedentary life greatly increases the risk of death in cancer patients

    • Last Update: 2022-01-23
    • Source: Internet
    • Author: User
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    According to the latest global cancer burden data released by the World Health Organization's International Agency for Research on Cancer (IARC) in 2020, there will be approximately 19.
    29 million new cancer cases and 9.
    96 million new cancer deaths worldwide in 2020
    .


    Among them, there were 4.


    Worldwide, as the population ages, the incidence of cancer will continue to increase
    .


    In addition, overweight/obesity, sedentary, physical inactivity, etc.


    Recently, Chao Cao et al.
    from Washington University School of Medicine published a research paper titled: Association of Daily Sitting Time and Leisure-Time Physical Activity With Survival Among US Cancer Survivors in the journal JAMA Oncology.

    JAMA OncologyJAMA Oncology Association of Daily Sitting Time and Leisure-Time Physical Activity With Survival Among US Cancer Survivors Association of Daily Sitting Time and Leisure-Time Physical Activity With Survival Among US Cancer Survivors

    The prospective cohort study of 1,535 cancer survivors with a median follow-up of 4.


    5 years found that those who were sedentary for longer had an increased risk of all-cause mortality, cancer mortality, and non-cancer mortality


    1535 Cancer Survivors 1535 Cancer Survivors People with more sedentary time increased all-cause mortality, cancer mortality, and non-cancer mortality risk of all-cause mortality, cancer mortality and increased risk of non-cancer mortality

    The results suggest that sedentary and physical inactivity, which is very common among cancer patients, is associated with an increased risk of death
    .

    Sedentary behavior, especially sedentary and physical inactivity, may affect cancer survivorship
    .


    Therefore, the research team wanted to study the association between daily sedentary time and physical activity and mortality in cancer patients


    Sedentary behavior, especially sedentary and physical inactivity, may affect cancer survivorship


    The results of statistical analysis showed that among the 1535 cancer patients, 950 (56.
    8%) had zero physical activity time (no exercise) in one week; 226 (15.
    6%) had less than 150 minutes of physical activity per week (insufficient exercise).
    ); 359 (27.
    6%) were physically active >150 min/week (actively active)
    .


    553 (35.


    During a follow-up period of up to 9 years (median follow-up 4.
    5 years), 293 of these 1535 died, 114 from cancer, 41 from heart disease, and 138 from other causes
    .

    Multivariate models showed that exercise was associated with a lower risk of all-cause mortality and cancer death compared with inactivity, specifically, exercise was associated with a 66% lower risk of all-cause mortality and a 68% lower risk of cancer death
    .

    Sitting more than 8 hours a day was associated with an 81% increased risk of all-cause death and a 127% increased risk of cancer death compared with those who sat for less than 4 hours a day
    .

    These analyses showed that prolonged sitting and insufficient physical activity were associated with a significantly increased risk of death in cancer patients
    .


    Cancer patients who were inactive or insufficiently active and who were sedentary for more than 8 hours a day had the highest risk of all-cause mortality and cancer mortality, increasing by 438% and 371%, respectively


    Overall, this cohort study of a nationally representative sample of cancer patients shows that sedentary and physical inactivity are very common and that this condition is associated with a substantially increased risk of all-cause mortality and cancer death


    Original source:

    Original source:

    Chao Cao, et al.


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