JAMA Oncol: monthly high dose vitamin D supplementation does not reduce cancer risk
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Last Update: 2018-07-26
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Source: Internet
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Author: User
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July 26, 2018 / biool / - Dr Robert Scragg and colleagues from the University of Auckland, New Zealand, conducted a causal analysis of data from the vitamin D assessment study, which recruited 5110 participants aged 50-84 who were randomly assigned to take vitamin D3 (2558 adults, initial dose 200000 IU, then 100000 IU per month or placebo (2552 people), with an average of 3.3 years, the researchers analyzed data from 5108 participants The researchers found that in 438 randomly selected participants, 25 hydroxyvitamin D levels in the serum of the vitamin D group were higher than those of the placebo group by more than 20 ng / ml The cancer rates of vitamin group and placebo group were 6.5% and 6.4%, respectively The adjusted hazard ratio was 1.01, the 95% confidence interval was 0.81-1.25, P = 0.95 "Taking high doses of vitamin D for up to four years a month without calcium does not prevent cancer either." The author wrote "This study suggests that further research is needed to explore the effect of taking it longer daily or weekly." Reference: Robert Scragg et al Monthly high dose vitamin D supply and cancer risk a post hoc analysis of the vitamin D assessment standardized clinical trial JAMA Oncol Published online July 19, 2018 Doi: 10.1001/jamaoncol.2018.2178
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