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    Home > Active Ingredient News > Study of Nervous System > JAMA Neurol: The risk of ischemic cerebrovascular events increased in patients with asymptomatic cervical arterial stenosis characterized by high-risk plaques in imaging.

    JAMA Neurol: The risk of ischemic cerebrovascular events increased in patients with asymptomatic cervical arterial stenosis characterized by high-risk plaques in imaging.

    • Last Update: 2020-08-25
    • Source: Internet
    • Author: User
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    The treatment of asymptomatic cervical stenosis patients is still controversial.
    Recently, researchers used high-risk plaque imaging characteristics to assess the incidence of ischemic cerebrovascular events in patients with asymptomatic cervical artery stenosis with high-risk plaques to establish the correlation and feasibility of risk-oriented blood transport reconstruction.
    this study is a systematic review and meta-analysis, collecting data from relevant studies as of July 31, 2019, with the main endpoints of the study as the prevalence of high-risk plaques and the annual occurrence of ischemic events in the same side.
    64 studies involving 20,751 participants in the 29-95 age range.
    , the combined prevalence of high-risk plaques was 26.5 percent among all participants.
    most common high-risk plaque features included: newborn blood vessels (785 cases), echo-clearing (12,364 cases), and lipid-rich necrosis core (3728 cases).
    The total occurrence rate of ischemic cerebrovascular events was 3.2 cases/100 patient years (22 queues, 10,381 participants; average follow-up period was 2.8 years), with side ischemicity in patients with high-risk plaques The occurrence rate of cerebrovascular events (4.3 cases/100 patient years) was higher than in patients without high-risk plaques (1.2 cases/100 patient years) and the risk ratio was 3.0 (I2 x 48.8%).
    In studies focusing on severe stenosis (9 cohorts, 2128 participants; average follow-up period 2.8 years), the occurrence rate of ischemic cerebrovascular events was 3.7 cases/100 years in patients with high-risk plaques The rate of hemocycular vascular events (7.3 cases/100 patient years) was also higher than in patients without high-risk plaques (1.7 cases/100 patient years) and the risk ratio was 3.2 (I2 x 39.6%).
    study, the proportion of patients with high-risk plaques was high in asymptomatic cervical stenosis patients, and high-risk plaques were associated with ischemic cerebrovascular events on the same side.
    .
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