JAMA Neurol: Multiple sclerosis patients should be alert to the risk of cardiovascular disease

small study found an increase in cardiovascular disease and mortality in patients with multiple sclerosis (MS), researchers recently conducted a population-based cohort study to assess the risk of large vascular events and death in patients with multiple sclerosisstudies were conducted in the UK between 1987 and 2018, with an average follow-up of 11.3 yearsA total of 12,251 MS patients and 72,572 non-MS patients participated, based on age, sex and general conditions, and the main results of the study were acute coronary artery syndrome, cerebrovascular disease, any large vascular disease (including peripheral artery disease) and mortality (all-cause mortality and cardiovascular-specific mortality), a total of 12,251 MS patients (66.9% female; average age of 44.9 years) of age, age of 44.9 years) and 72,572 non-MS patients (69.8% female; average age of SD), 44.9 years oldCompared to non-MS patients, the risk of acute coronary syndrome increased by 28% (risk compared to HR, 1.28), 59% increased risk of cerebrovascular disease (HR: 1.59), 32% increase in the risk of vascular disease (HR: 1.32), 3.5 times increased all-cause mortality (HR: 3.46), and cardiovascular mortality increased by 1.5 times (HR, 1.47)The difference in large vascular events was more pronounced in women than in men, and the mortality rate was higher among women than in menIn patients with MS, taking lipid-reducing drugs (mainly statins) can reduce mortalitystudies suggest that patients with multiple sclerosis have an increased risk of cardiovascular disease, which is not fully explained by traditional vascular risk factors