JAMA Neurol: Delirium is an important risk factor for long-term cognitive decline.
-
Last Update: 2020-07-17
-
Source: Internet
-
Author: User
Search more information of high quality chemicals, good prices and reliable suppliers, visit
www.echemi.com
!---- delirium can lead to increased medical expenses, complications, and mortality, and researchers recently looked at the association between delirium and long-term cognitive declinethis study is a systematic review and meta-analysis of data from January 1, 1965 to December 31, 2018, with key words including delirium and postoperative cognitive dysfunction; delirium and cognitive impairment; delirium and dementia; and delirium and memoryThe main endpoint of thestudy was the decline in cognitive ability of the delirium group compared to those who had no delirium experiencethe study included data from 23 studies, including 3,562 delirium patients and 6,987 delirium-free control groupsstudy found a significant association between delirium and long-term cognitive decline, with the estimated effect size (Hedges g) in 23 studies at 0.45in all studies, patients who experienced delirium had poorer cognitive ability in the last evaluation nodeThe I2 value for heterogeneity betweenstudies is 0.81multivariate metaregression analysis shows that follow-up time (longer, gs is larger), the number of covariates controlled (more number, less gs), and baseline cognitive matching (matching with largegs) are the main factors of biassubgroup and meta-regression analysis show that delirium may be the cause of cognitive declinestudies have found a significant correlation between delirium and long-term cognitive decline.
This article is an English version of an article which is originally in the Chinese language on echemi.com and is provided for information purposes only.
This website makes no representation or warranty of any kind, either expressed or implied, as to the accuracy, completeness ownership or reliability of
the article or any translations thereof. If you have any concerns or complaints relating to the article, please send an email, providing a detailed
description of the concern or complaint, to
service@echemi.com. A staff member will contact you within 5 working days. Once verified, infringing content
will be removed immediately.
