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Spouses often share a common environment, and many studies have investigated spousal concordance factors, such as life>
.
Therefore, these factors may mediate the associated cognitive impairment and changes in cognitive function between couples
prevention
Hee Won Yang et al .
published a research article in JAMA Network Open magazine to explore the factors that affect couples' cognitive decline and their mediating role in the joint risk of cognitive impairment and cognitive function in couples
.
This prospective cohort study followed 784 participants every two years and included older couples and their spouses (KLOSCAD-s) from the Korean Longitudinal Study of Cognitive Aging and Dementia (KLOSCAD)
.
Cognitive impairment in spouses was defined as mild cognitive impairment or dementia
The study included 784 KLOSCAD participants (307 women [39.
2%], 477 men [60.
8%]; mean [SD] age (74.
8 [4.
8] years) and spouses (477 women [60.
8%] and 307 male [39.
2%]; mean [SD] age, 73.
6 [6.
2] years)
.
In the KLOSCAD-s cohort, cognitive impairment in KLOSCAD participants was nearly fold associated with their spouse's risk of cognitive impairment (odds ratio, 1.
History of head injury (β = 0.
50; 95% confidence interval, 0.
09 - -0.
90; P = 0.
02) and age (β = 2.
57; 95% confidence interval, 1.
37 - -3.
76; P < 0.
001) mediated between KLOSCAD participants The association between cognitive impairment and the risk of cognitive impairment in their spouses
.
Physical inactivity mediated this association through major depressive disorder (physical inactivity β = 0.
History of head injury (β = 0.
The environment in which couples live together may contribute to the common cognitive impairment and cognitive performance of couples
.
Identifying and intervening on common risk factors for dementia between couples may reduce the risk of cognitive impairment in spouses of people with dementia
The environment in which couples live together may contribute to the common cognitive impairment and cognitive performance of couples
original source original source
Yang HW, Bae JB, Oh DJ, et al.
https://jamanetwork.
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