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JAMA Netw Open: Are prostate cancer drugs gonadotropin-releasing hormone agonists associated with cardiovascular disease risk and hypertension in men with diabetes?

 Last Update: 2022-08-19
 Source: Internet
 Author: User

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Prostate cancer (PCa) is one of the most common cancers in men, with more than 1 million men diagnosed with prostate cancer worldwide in 2019. Men with PCa have a higher risk of cardiovascular disease (CVD) than men without PC.

Studies have pointed to an increased risk of cardiovascular disease (CVD) in men with type 2 diabete.

The study was a population-based cohort design and included longitudinal data from 2006 to 2016. Using these data, the researchers established 2 large cohorts consisting of men with and without PCa and men with and without GnRH agonist.

The PCa cohort included 5714 men (median [IQR] age, 70 [10]) and the non-PCa cohort included 28,445 PCa-free men (median [IQR] age, 70 [10].

Cumulative incidence of cardiovascular disease

In conclusion, in this population-based cohort study, men with type 2 diabetes who received GnRH agonists for PCa had an increased risk of CV.

Original source:

E Lin, Hans Garmo, Mieke Van Hemelrijck et a.

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