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    Home > Active Ingredient News > Study of Nervous System > JAMA has posted a reminder! Postpartum depression can significantly affect infant speech development

    JAMA has posted a reminder! Postpartum depression can significantly affect infant speech development

    • Last Update: 2022-10-20
    • Source: Internet
    • Author: User
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    *For medical professionals only, read and refer
    to put aside all bad emotions!



    Executive summary



    On September 27, 2022, a new study published in JAMA showed that maternal postpartum depression appeared to be associated
    with infants' verbal perception trajectories.

    Research screenshots

    status quo



    Gesa Schaadt, PhD, and colleagues at Freie Universitt, Berlin, Germany, said:
    • The development of mismatch responses (usually from positive to more negative values) stagnated or even became more positive (immature) at 6.
      5 months
      , the mother's mood was more depressed, and this association became significant at an EPDS score of 8.
      57 or higher;

    • The foundations of language development are already established in the first weeks of life and are based on speech perception, with early interruptions increasing the risk of language difficulties later in life;
    • Our findings expand on previous reports of a negative association between maternal postpartum clinical depressed mood and children's language development by exploring the subclinical range
      of maternal mood.
      Consistent with previous research, a reduction in infant-guided speech use in depressed mothers was associated with children's developmental trajectories;

    • Infant directed speech uses greater pitch variability and slower speaking rate compared to adult directed speech, which is essential
      to encourage early language perception.
      However, depressed mothers often show a decrease
      in the tone of their voices when directing speech to their babies.


    conclusion



    The authors recruited 46 healthy pairs of German mother-baby twins from January 2018 to October 2019
    from the Max Planck Institute for Human Cognitive and Brain Sciences database.
    The average age of the mother was 32 years, she was not a smoker and had no history of
    neurotoxin use.
    All mothers were on maternity leave throughout the study period and were part of
    a joint family with two parents.
    When their babies were 2 months old, they reported postpartum emotions
    through the German version of EPDS.

    Scores range from 1 to 30, with higher scores indicating higher levels of depressed mood and a cut-off value of 13 indicating a higher
    probability of clinical depression.
    Electrophysiological correlation
    (mismatched response to verbal stimuli)
    of infants' speech perception was tested at infants 2 and 6.
    5 months.
    At an initial assessment of 2 months and 6.
    5 months follow-up, the infant was evenly distributed
    between boys and girls.
    Exclusion criteria for infants include gestational age less than 37 weeks, birth weight less than 2700 g, and a diagnosis of
    hearing defects or neurological disorders.


    The results are displayed



    In a sample of 46 mothers, depression subclinical postpartum mood [mean (EPDS) score of 4.
    8] was associated
    with weaker longitudinal changes in infants.

    From infants 2~6.
    5 months, the brain responds electrophysiological to syllabic pitch speech information
    (coefficient 0.
    68, 95% CI 0.
    03-1.
    33, =0.
    04).

    Although modest analysis of consonant, vowel, and vowel length mismatch responses could not significantly explain the population variance, it only significantly explained the population variance of syllable pitch mismatch responses
    (0.
    12, 95% CI 0.
    00-0.
    32, =0.
    04), and the intercept was not significant (coefficient -2.
    41, 95% CI 0.
    03-1.
    33, =0.
    04).

    。 It is shown that between 2~6.
    5 months, the mismatch reaction changes from positive amplitude to negative amplitude
    .


    prospect



    Schaadt and team say:
    • Over time, correlation does not imply causation
      .
    • In addition, there was no test for the mother's high range of vocalizations, which was a limitation, and the study only assessed the mother's mood
      when the baby was 2 months old.


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